How many Tepezza infusions are used?

The label describes 8 infusions. They are given with the first dose lower and later doses every 3 weeks [1] .

Can Tepezza affect hearing?

Yes. The label warns about hearing impairment, including severe cases [1] .

Can I use Tepezza while pregnant?

The label warns that Tepezza can cause fetal harm. Pregnancy testing and contraception guidance are part of safety planning [1] .

Will I still need thyroid eye surgery?

Maybe. Some people still need eyelid, eye muscle, or orbital surgery after the disease is stable.

Treatment

Tepezza

Also known as Teprotumumab-trbw, Thyroid Eye Disease Infusion, TED Infusion, Graves Eye Disease Treatment, Teprotumumab Infusion

Updated May 18, 2026·For educational purposes only. Not a substitute for medical advice. See our terms.

Bottom Line

Tepezza is an infusion medicine for thyroid eye disease. It can reduce eye bulging and double vision for selected patients, but it needs careful safety screening.

Tepezza is teprotumumab-trbw. The prescribing label lists it for thyroid eye disease regardless of disease activity or duration ¹.

The usual course is 8 intravenous infusions. The first dose is lower, then later doses are given every 3 weeks ¹.

The label warns about infusion reactions, inflammatory bowel disease flares, high blood sugar, hearing problems, and fetal harm ¹.

How It Works

Tepezza is an antibody medicine. It blocks a growth-factor receptor involved in thyroid eye disease activity ¹.

It is given into a vein in an infusion center. It is not an eye drop or eye injection.

Who It Helps

Tepezza may be considered when thyroid eye disease causes bulging, swelling, pain, redness, or double vision.

An eye specialist confirms the diagnosis.
Safety risks are reviewed before starting.
Pregnancy is avoided during and after treatment as directed.
Blood sugar, hearing, and bowel symptoms can be monitored.

Side Effects and Safety

The label warns about infusion reactions, bowel disease flares, high blood sugar, hearing problems, and fetal harm ¹.

Tell your team right away about hearing change, ringing, severe diarrhea, severe stomach pain, or high blood sugar symptoms.

Cost and Insurance

Tepezza is a specialty infusion drug. Prior authorization is common.

Ask whether the drug, infusion center, lab tests, and specialist visits are billed separately.
Ask what documentation the plan needs.
Ask about manufacturer support only through official program channels.
Confirm out-of-pocket cost before the first infusion.

Common Questions About Tepezza

No. Tepezza is given as an intravenous infusion in a medical setting.

Next Steps

1Ask an oculoplastics or neuro-ophthalmology specialist to confirm thyroid eye disease.
2Review blood sugar, hearing, bowel disease, and pregnancy risks before treatment.
3Confirm infusion schedule and monitoring visits.
4Ask the office to complete insurance authorization before the first infusion.
5Report hearing change, severe diarrhea, or high blood sugar symptoms promptly.

Find specialists for Tepezza

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