Miebo
Also known as Perfluorohexyloctane, Perfluorohexyloctane Eye Drops, Miebo Eye Drops, Anti-Evaporative Dry Eye Drop, Water-Free Dry Eye Drop
Bottom Line
Miebo is a prescription dry eye drop that helps slow tear evaporation. It is most often used when poor eyelid oil makes tears dry up too fast.
Miebo (perfluorohexyloctane) is a water-free prescription eye drop. It spreads over the tear film and helps reduce evaporation. The current label lists it for signs and symptoms of dry eye disease 1.
Many people with evaporative dry eye have meibomian gland dysfunction. That means the eyelid oil glands do not release a healthy oil layer. Without that layer, tears evaporate too fast 2.
Phase 3 studies of perfluorohexyloctane found improvement in corneal staining and dryness symptoms. Long-term extension data also supported tolerability over 52 weeks 3.
How Miebo Works
A healthy tear film has a thin oil layer on top. That oil layer slows evaporation. When the eyelid oil glands do not work well, tears can dry up too fast.
Miebo is made of perfluorohexyloctane. It is an anti-evaporative prescription treatment for dry eye disease. It spreads over the tear film to reduce evaporation instead of adding watery tears 4.
Who It Helps
Miebo may help when dry eye is driven by tear evaporation.
- Burning or dryness happens daily.
- Artificial tears help only briefly.
- The eyelid oil glands are blocked or poor quality.
- Screen work, wind, or dry air worsens symptoms.
- The cornea shows dryness staining.
It may not be enough by itself if inflammation, eyelid disease, allergy, or severe aqueous tear deficiency is the main driver.
Side Effects
Miebo is generally well tolerated. The label lists blurred vision as the most common ocular adverse reaction 1.
- Temporary blur. This can happen right after a drop.
- Unusual drop feel. The drop may feel oily or different from artificial tears.
- Allergy or irritation. Stop and call the doctor for swelling, rash, or worsening redness.
Remove contact lenses before dosing. Follow the label or your doctor's instructions before putting lenses back in.
Cost and Insurance
Miebo is a brand-name prescription drop. Coverage varies by pharmacy benefit plan.
- Your plan may require prior authorization.
- Some plans require trying artificial tears or another prescription first.
- Manufacturer savings programs may lower copays for eligible commercial insurance.
- Medicare and cash prices vary by pharmacy and plan rules.
Ask the pharmacy for the cash price, covered price, and any prior authorization steps before you leave the office.
Common Questions About Miebo
Next Steps
- 1Book a dry eye exam to confirm whether tear evaporation is a major driver.
- 2Ask how Miebo fits with warm compresses, lid cleaning, and other drops.
- 3Check insurance coverage and prior authorization before filling the prescription.
- 4Remove contact lenses before using Miebo and follow the label timing.
- 5Call your eye doctor for worsening redness, pain, light sensitivity, or vision loss.
Find specialists for Miebo
Board-certified ophthalmologists who treat Miebo.
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