Combigan (brimonidine + timolol)
Also known as Brimonidine Timolol, Combigan Eye Drops, Combination Glaucoma Drop, Twice-Daily Eye Pressure Drop
Bottom Line
Combigan combines brimonidine and timolol in one bottle. It can simplify treatment, but it is not safe for everyone.
Combigan is a combination of brimonidine tartrate and timolol maleate. The label lists it for high eye pressure in glaucoma or ocular hypertension when pressure is not controlled well enough 1.
The label dose is one drop in the affected eye two times daily, about 12 hours apart 1.
Combigan is not used in babies younger than 2 years. It is also not for people with asthma, severe chronic lung disease, slow heartbeat, heart block, heart failure, or cardiogenic shock.
Cost and Insurance
Combigan is a brand-name combination drop. Some plans may prefer separate generic brimonidine and timolol bottles first.
Ask whether one bottle lowers your copay or whether separate bottles are less expensive.
How It Works
Combigan combines brimonidine and timolol. The two medicines lower eye pressure in different ways.
One bottle can be easier than two. It still has safety concerns from both ingredients.
Who Should Avoid It
The label says Combigan is not for babies younger than 2 years. It is also not for people with asthma or severe chronic lung disease. Other reasons include slow heartbeat, heart block, heart failure, cardiogenic shock, or allergy to any component 1.
Tell your doctor about low blood pressure, depression, diabetes medicines, thyroid disease, and planned surgery.
Side Effects
The label lists allergic conjunctivitis, surface follicles, eye redness, itching, burning, and stinging as common reactions 1.
Call your doctor for wheezing, fainting, chest pain, severe sleepiness, swollen lids, or worsening vision.
Common Questions About Combigan
Next Steps
- 1Tell your doctor about asthma, lung disease, heart rhythm problems, and low blood pressure symptoms.
- 2Use Combigan about 12 hours apart unless your doctor gives another plan.
- 3Separate other eye drops by at least 5 minutes.
- 4Call for wheezing, fainting, chest pain, severe sleepiness, or swollen lids.
- 5Keep pressure checks to confirm the combination is working.
Find specialists for Combigan (brimonidine + timolol)
Board-certified ophthalmologists who treat Combigan (brimonidine + timolol).
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